Patient safety has been demonstrated in 10 clinical trials

Periowave is safe for use on restorative materials, inlays, crowns, bridges, prostheses, sealants and implants. Periowave safely removes pathogens without:

  • Charring roots or gingival tissue
  • Promoting antibiotic resistance
  • Completely destroying commensal bacteria
  • Causing pain or side effects
  • Requiring any patient compliance or much chair time

There have been no observed serious adverse events with Periowave in clinical testing on more than 100,000 treatments. However, there remains the potential for an adverse reaction in the following patients:

  • Patients currently on systemic photosensitizing medications
  • Patients with severe glucose-6-phosphate dehydrogenase (G6PD) deficiency.
  • Patients with allergies / hypersensitivity to methylene blue or polymethyl methacrylate (PMMA).
  • Patients with allergies / hypersensitivity to chlorhexidine.

Patients may notice a slight blue color on or near the treated teeth related to residual photosensitizing solution. This is harmless and should disappear quickly.